Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Dental Opioid Prescriptions & Subsequent Abuse

JAMA Intern Med; ePub 2018 Dec 3; Schroeder, et al

Among adolescents and young adults, dental opioid prescriptions written for pain management of third molar extractions, may be associated with subsequent opioid use and abuse. This according to a retrospective cohort study that examined the association between index dental opioid prescriptions from dental clinics for opioid-naïve adolescents and young adults in 2015 and new persistent use and subsequent diagnosis of abuse in this population. Among the findings:

  • Among 754,002 individuals with continuous enrollment in 2015, 97,462 patients (12.9%) received ≥1 opioid prescriptions, of whom 29,791 (30.6%) received prescriptions supplied by a dental clinician.
  • Index opioid prescriptions in opioid-naïve adolescents and young adults were associated with a statistically significant 6.8% absolute risk increase in persistent opioid use and a 5.4% increase in the subsequent diagnosis of opioid abuse.
  • There was only 1 death in each cohort.

Citation:

Schroeder AR, Dehghan M, Newman TB, Bentley JP, Park KT. Association of opioid prescriptions from dental clinicians for US adolescents and young adults with subsequent opioid use and abuse. [Published online ahead of print December 03, 2018]. JAMA Intern Med. doi:10.1001/jamainternmed.2018.5419.

Must Reads in Pain

Sleep Disturbance and Chronic Pain Intensity, Clin J Pain; ePub 2019 Mar 25; Burgess, et al

Dual Receipt of Rx Opioids & Overdose Death, Ann Intern Med; ePub 2019 Mar 12; Moyo, et al

Opioid-Related Mortality in US by Opioid Type, JAMA Netw Open; 2019 Feb 22; Kiang, et al

Disparities in the Prescription of Opioids, JAMA Intern Med; ePub 2019 Feb 11; Friedman, et al

Trends in Pain Prevalence in US Adults, J Pain; ePub 2019 Jan 15; Nahin, et al