Overall antibiotic use and potentially inappropriate use remained relatively steady among US older adults in 2011-2015, but the use of individual antibiotics saw divergent changes in use, a recent study found. The observational study used US Medicare administrative claims in 2011-2015 and examined overall rates of antibiotic prescription claims, rates of potentially appropriate and inappropriate prescribing, rates for each of the most frequently prescribed antibiotics, and rates of antibiotic claims associated with specific diagnoses. Researchers found:
- The number of antibiotic claims fell from 1364.7 to 1309.3 claims per 1,000 beneficiaries per year in 2011-2014 (adjusted reduction of 2.1%), but then rose to 1364.3 claims per 1,000 beneficiaries per year in 2015 (adjusted reduction of 0.20%).
- Potentially inappropriate use of antibiotics decreased slightly in 2011-2014 (3.9%).
- However, prescribers’ use of individual antibiotics had no consistent association with guideline changes.
Olesen SW, Barnett ML, MacFadden DR, Lipsitch M, Grad YH. Trends in outpatient antibiotic use and prescribing practice among US older adults, 2011-15: Observational study. [Published online ahead of print July 27, 2018]. BMJ. doi:10.1136/bmj.k3155.
This Week's Must Reads
Must Reads in Infectious Diseases
Rapid Point of Care Test for Influenza, J Am Board Fam Med; 2019 Mar; Dale, et al
Invasive GBS Infections in Nonpregnant US Adults, JAMA Intern Med; ePub 2019 Feb 18; Francois Watkins, et al
Prescribed Opioids & Risk of CAP in Patients with HIV, JAMA Intern Med; 2019 Jan 7; Edelman, et al
Influenza Vaccination Safety During Hospitalization, Mayo Clin Proc; ePub 2019 Jan 8; Tartof, et al
Hospitalization Trends for Drug-Use Associated IE, Ann Intern Med; ePub 2018 Dec 4; Schranz, et al