In older women, both high sedentary time and long mean bout durations were associated in a dose-response manner with increased cardiovascular disease (CVD) risk, a new study found. Women from the Objective Physical Activity and Cardiovascular Health (OPACH) study (n=5,638, aged 63‒97 years) with no history of myocardial infarction (MI) or stroke wore accelerometers for 4 to 7 days and were followed up for up to 4.9 years for CVD events. Researchers found:
- There were 545 CVD events during 19,350 person-years.
- Women with the highest vs lowest quartile of sedentary time had higher risk for CVD (HR, 1.62), after adjustment for covariates.
- Longer vs shorter mean sedentary bout duration was associated with higher risk for CVD (HR, 1.54), after adjustment for covariates.
- Women jointly classified as having both high sedentary time and long bout duration had significantly higher risk for CVD (HR, 1.34) vs women with low sedentary time and short bout duration.
Bellettiere J, LaMonte MJ, Evenson KR, et al. Sedentary behavior and cardiovascular disease in older women. The OPACH Study. Circulation. 2019;139:1036-1046. doi:10.1161/CIRCULATIONAHA.118.035312.
This Week's Must Reads
Acute Illness and Cannabis Use in Adults, Ann Intern Med; ePub 2019 Mar 26; Monte, et al
Pregnancy History and Risk of Miscarriage, BMJ; ePub 2019 Mar 20; Magnus, et al
Firearms Mortality Among US Schoolchildren, Am J Med; ePub 2019 Mar 25; Rubenstein, et al
Rapid Point of Care Test for Influenza, J Am Board Fam Med; 2019 Mar; Dale, et al
Sleep Disturbance and Chronic Pain Intensity, Clin J Pain; ePub 2019 Mar 25; Burgess, et al
Must Reads in Cardiology
Consumption of SSBs & Risk of Mortality, Circulation; ePub 2019 Mar 18; Malik, et al
Dietary Cholesterol or Egg Consumption & CVD, JAMA; 2019 Mar 19; Zhong, Van Horn, et al
Physical Activity & Incidence of CHD & CVD in Women, JAMA Netw Open; ePub 2019 Mar 15; LaCroix, et al
Intensive BP Control in Adults with Hypertension Who Smoke, JAMA Netw Open; ePub 2019 Mar 8; Scarpa, et al
Leisure-Time Physical Activity Across Adulthood, JAMA Netw Open; ePub 2019 Mar 8; Saint-Maurice, et al