Clinical Edge

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TNF inhibitor prices rose despite increased drug class competition

San-Juan-Rodriguez A et al. JAMA Intern Med. 2019 Feb 18. doi: 10.1001/jamainternmed.2018.7656

Key clinical point: Market failure is contributing to the rising costs of prescription drugs.

Major finding: If cost trends had not changed after the entry of new TNF inhibitors after 2009, the costs of etanercept, infliximab, and adalimumab in December 2016 would have been 40%-45% lower.

Study details: An interrupted time series analysis of payment data during 2006-2016 with a linear model that calculated the trends in costs that would have been expected if three new anti-TNFs had not entered the market after 2009.

Disclosures: The study was funded in part by the Myers Family Foundation and one author reported funding from the National Heart, Lung, and Blood Institute.

Citation:

San-Juan-Rodriguez A et al. JAMA Intern Med. 2019 Feb 18. doi: 10.1001/jamainternmed.2018.7656

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TNF inhibitor prices rose despite increased drug class competition, San-Juan-Rodriguez A et al. JAMA Intern Med. 2019 Feb 18. doi: 10.1001/jamainternmed.2018.7656

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