Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

This Week's Must Reads

HRRP & Patient Mortality in HF, AMI & Pneumonia, JAMA; 2018 Dec 25; Wadhera, et al

Hypertensive Diseases of Pregnancy & Risk of HF, Mayo Clin Proc; ePub 2018 Dec 19; Nizamuddin, et al

Clopidogrel + Aspirin Can Reduce Recurrent Stroke, BMJ; ePub 2018 Dec 18; Hao, Tampi, et al

Second-Line ADMs & CV Events in T2D, JAMA Netw Open; ePub 2018 Dec 21; O’Brien, et al

Health Care Utilization of a Dementia Care Program, JAMA Intern Med; ePub 2018 Dec 21; Jennings, et al

Clinical Guidelines

USPSTF: Interventions to Prevent Child Maltreatment, JAMA; 2018 Nov 27; US Preventive Services Task Force

Cholesterol Guidelines Stress Lifetime Approach, Circulation; ePub 2018 Nov 10; Grundy, et al

Read more in Clinical Guidelines

FDA Actions

FDA Approves Ajovy for Migraine in Adults, Teva Pharmaceutical news release; 2018 Sep 14

FDA Approves Steglatro for Adults with T2D, Pfizer news release; 2017 Dec 22

Read more in FDA Actions

Geriatrics

Site of Death & Patterns of Care in Older Adults, JAMA; ePub 2018 Jun 25; Teno, Gozalo, et al

Psychological Interventions & Chronic Pain Reduction, JAMA Intern Med; ePub 2018 May 7; Niknejad, et al

Read more in Geriatrics

Pediatrics

Trends in Pediatric Outpatient Antibiotic Use, Pediatrics; ePub 2018 Dec 17; Finkelstein, et al

Predicting Asthma Development in Young Children, J Allergy Clin Immunol; ePub 2018 Dec 13; Biagini Myers, et al

Read more in Pediatrics

Cardiology

HRRP & Patient Mortality in HF, AMI & Pneumonia, JAMA; 2018 Dec 25; Wadhera, et al

Hypertensive Diseases of Pregnancy & Risk of HF, Mayo Clin Proc; ePub 2018 Dec 19; Nizamuddin, et al

Read more in Cardiology

Asthma

Fractional Exhaled Nitric Oxide Testing in Asthma, Mayo Clin Proc; ePub 2017 Dec 20; Wang, et al

Pharmacologic Tx of Seasonal Allergic Rhinitis, Ann Intern Med; ePub 2017 Nov 28; Wallace, et al

Read more in Asthma

Oncology

Does Vitamin D Reduce Cancer & CVD Risk?, N Engl J Med; ePub 2018 Nov 10; Manson, et al

Interventions to Increase CRC Screening Rates, JAMA Intern Med; ePub 2018 Oct 15; Dougherty, et al

Read more in Oncology

Rheumatology

Screening for Osteoporosis to Prevent Fractures, JAMA; ePub 2018 Jun 26; US Preventive Services Task Force

Psychological Interventions & Chronic Pain Reduction, JAMA Intern Med; ePub 2018 May 7; Niknejad, et al

Read more in Rheumatology

Vaccines

Acellular Pertussis Vaccine Is Safe & Effective, JAMA Pediatr; 2018 Nov; Wood, Nolan, et al

Influenza and Pertussis Vaccination in Pregnancy, Vaccine; ePub 2018 Nov 3; Wilcox, Bottrell, et al

Read more in Vaccines

Trauma

Linking Traumatic Events & Pain Severity, J Pain; ePub 2016 Sep 15; Nicol, Sieberg, et al

Read more in Trauma

Obesity

Lifestyle Modification Advice Among HCPs, Am J Med; ePub 2018 Dec 3; Grabovac, et al

Is Obesity Associated With Adverse CV Outcomes?, JAMA Netw Open; 2018 Nov 16; Riaz, et al

Read more in Obesity

Men's Health

USPSTF: Screening for Prostate Cancer, JAMA; 2018 May 8; Grossman, et al

Protein Intake & Lean Body Mass in Older Men, JAMA Intern Med; ePub 2018 Mar 12; Bhasin, et al

Read more in Men's Health

Neurology

Health Care Utilization of a Dementia Care Program, JAMA Intern Med; ePub 2018 Dec 21; Jennings, et al

Smoking and Risk of Ischemic Stroke in Young Men, Stroke; ePub 2018 Apr 19; Markidan, et al

Read more in Neurology

Health Policy

Multimorbidity Trends Among US Adults, J Am Board Fam Med; 2018 Jul-Aug; King, et al

ACP Position on Women’s Health Challenges, Ann Intern Med; ePub 2018 May 29; Daniel, et al

Read more in Health Policy

Preventive Care

Midlife Death Rates Among Racial & Ethnic Groups, BMJ; ePub 2018 Aug 15; Woolf, Chapman, et al

Preventability of Early vs Late Readmissions, Ann Intern Med; ePub 2018 May 1; Graham, et al

Read more in Preventive Care