Irritable Bowel Syndrome: Evidence-based Treatment

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IBS is a commonly occurring disorder of heterogeneous nature and pathogenesis. Therefore, basing a diagnosis on the presenting symptoms is not ideal; using clinical criteria to make a determination is more accurate. Once the diagnosis is made, IBS can be categorized into subtypes according to bowel function: diarrhea, constipation, or mixed. Knowing the subtype may guide the clinician in recommending a treatment, eg, patients with IBS-D may benefit from loperamide and those with IBS-C find relief with lubiprostone. The range of treatment strategies includes making lifestyle changes (eg, diet and exercise); incorporating CBT; and prescribing neuromotility agents and probiotics.

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