Genetic factors contribute to a single spectrum of traumatic stress reflecting resilience at one end and high symptom severity at the other, according to a recent study. To that end, rather than focusing only on genetic risk for posttraumatic stress syndrome (PTSD), molecular genetics research may benefit from evaluation of the broader spectrum of traumatic stress. A classical twin study of 2010–2012 survey data was conducted among 3,318 male twin pairs in the Vietnam Era Twin Registry. Analyses included: (a) estimates of genetic and environmental influences on PTSD symptom severity and resilience; (b) development of a latent model of traumatic stress, spanning both PTSD and resilience; and (c) estimates of genetic and environmental influences on this spectrum. Researchers found:
- The heritability of PTSD was 49% and of resilience was 25%.
- PTSD and resilience were correlated at r = –.59, and 59% of this correlation was attributable to a single genetic factor, whereas the remainder was due to a single non-shared environment factor.
Wolf EJ, Miller MW, Sullivan DR, et al. A classical twin study of PTSD symptoms and resilience: Evidence for a single spectrum of vulnerability to traumatic stress. [Published online ahead of print December 28, 2017]. Depress Anxiety. doi:10.1002/da.22712.
This Week's Must Reads
Contraceptive Choice Among Young Adults Examined, J Sex Res; ePub Jan 26; Harvey, Oakley, et al
Depression Symptoms During/After Postpartum Phase, Depress Anxiety; ePub 2018 Feb 2; Fox, Sandman, et al
Caregivers of PLWDs at Risk for Sleep Disturbances, Am J Geriatr Psych; ePub 2018 Feb 4; Polenick, et al
Axis II Comorbidities in BD: Mood State Matters, Bipolar Disord; ePub 2018 Jan 25; Post, et al
Religion, Porn, Sexual Satisfaction Link Examined , J Sex Res; ePub 2018 Jan 29; Perry, Whitehead
Must Reads in PTSD
Written Exposure Therapy Efficacious for PTSD , JAMA Psychiatry; ePub 2018 Jan 17; Sloan, et al
Depression 14-15 Years After 9/11 Terror Attacks , J Affect Disord; ePub 2018 Jan 3; Jacobson, et al
PTSD, Genetic Factors, and Resilience Examined, Depress Anxiety; ePub 2017 Dec 28; Wolf, et al
Symptom Clusters’ Links to Psychiatric Disorders, JAMA Psychiatry; ePub 2017 Dec 3; Grisanzio, et al
Physical Health Conditions Linked to PTSD in Vets, J Affect Disord; ePub 2017 Nov 15; El-Gabalawy, et al