The California Learning Verbal Test II (CVLT II) and the Open Trial-Selective Reminding Test (OT-SRT), used to assess learning in persons with multiple sclerosis (MS), are not equivalent tests, according to a recent comparison study. While the CVLT II appears to be sensitive to overall cognitive dysfunction, the OT-SRT is more sensitive to focal learning and memory impairments. 112 participants with MS performed both tests. All completed additional cognitive tests assessing information processing speed (IPS), working memory (WM), and executive functions (EF). All participants were identified as having impaired learning on the OT-SRT; however, only 38 participants (33.9%) were identified as having impaired learning on the CVLT II. The sample was thus divided into 2 groups, those who failed both tests (Fail-2) and those who failed only 1 (Fail-1). Researchers found:
- The Fail-2 group showed poorer performance on EF, WM and IPS in comparison with the Fail-1 group.
- On the CVLT II, the Fail-1 group showed a significantly greater improvement between trials 1 and 5, as compared with the Fail-2 group.
Costa SL, DeLuca J, Costanza K, Chiaravalloti ND. Comparing the open trial – Selective reminding test results with the California Learning Verbal Test II in multiple sclerosis. [Published online ahead of print April 4, 2018]. Appl Neuropsychol Adult. doi:10.1080/23279095.2018.1448818.
This Week's Must Reads
Hospital Readmission After Seizure Discharge, Neurology; ePub 2018 Dec 21; Blank, et al
VP Shunts and Post-Operative Complications Assessed, J Stroke Cerebrovasc Dis; ePub 2018 Dec 20; Linzey, et al
Disparities in Inter-Hospital Helicopter Transport, J Stroke Cerebrovasc Dis; ePub 2018 Dec 11; Sarrazin, et al
Mild-to-Moderate OSA Linked with Hypertension, Sleep; ePub 2018 Dec 22; Vgontzas, et al
Aspirin Reduces Stroke Risk in Women with Prior HDP, Neurology; ePub 2018 Dec 26; Miller, Boehme, et al
Must Reads in Multiple Sclerosis
Prevalence of Asthma in Persons with MS, Mult Scler Relat Disord; ePub 2018 Dec 11; Hill, et al
Normal-Appearing White Matter in MS Examined, Neuroradiology; ePub 2018 Dec 12; Yu, et al
MS Disease Burden: Which Symptoms Matter Most?, Mult Scler Relat Disord; 2018 Oct; Barin, et al
Retinal Layer Thickness and MS Conversion Risk, Mult Scler; ePub 2018 Dec 3; Filippatou, et al
Importance of Coping and QOL in People with MS, Int J MS Care; ePub 2018 Dec 6; Grech, et al