In a large, population-based multiple sclerosis (MS) cohort, researchers found stable incidence and increasing prevalence of MS. Furthermore, a spike in incidence in 2010 among younger patients and men at a time of widespread media coverage of MS suggests that these groups may be vulnerable to delayed diagnosis. Researchers identified MS cases from 1996 to 2013 by applying a validated algorithm to health administrative data. They found:
- The prevalence of MS increased by 69% from 1.57 per 1,000 in 1996 (n=12,155) to 2.65 in 2013 (n=28,192).
- Incidence remained relatively stable except for a spike in 2010, followed by a subsequent decline in 2011–2013, particularly among young people and men.
- Mortality decreased by 33% from 26.7 per 1,000 to 18.0 per 1,000.
- The incidence sex ratio was stable from 1996 to 2009, then declined in 2010, with partial rebound by 2013.
Rotstein DL, Chen H, Wilton AS, et al. Temporal trends in multiple sclerosis prevalence and incidence in a large population. [Published online ahead of print March 16, 2018]. Neurology. doi:10.1212/WNL.0000000000005331.
This Week's Must Reads
PD Global Burden More than Doubles, from 1990-2016, Lancet Neurol; ePub 2018 Oct 1; Dorsey, et al
Disparities Found in Dementia Medication Use for PD, JAMA Neurol, ePub 2018 Oct 1; Mantri, Fullard, et al
Gray Matter Abnormalities in Movement Disorders, Neurology; ePub 2018 Oct 10; Maurer, LaFaver, et al
Periodic Limb Movements in Sleep Increase with Age, Clin Neurophysiol; 2018 Nov; Leary, Moore IV, et al
Cognitive Ability Assessment Tool Proves Effective, Mov Disord; ePub 2018 Oct 10; Holden, Medina, et al
Must Reads in Multiple Sclerosis
Aerobic Exercise May Improve Cognition in MS, Mult Scler Relat Disord; ePub 2018 Oct 3; Sandroff, et al
Project ECHO Delivers MS Care in Underserved Areas, Int J MS Care; ePub 2018 Oct 4; Alschuler, et al
Use of eHealth Technologies Common in MS Community, Mult Scler Relat Disord; ePub 2018 Oct 3; Marrie, et al
Probability Discounting of MS Treatment Decisions, Psychopharmacology; ePub 2018 Sep 22; Bruce, et al
ADSTEP May Increase Walking in Persons with MS, Arch Phys Med Rehab; 2018 Oct; Martini, et al