Anxiety without comorbid depression is associated with less risk of falling, even when comparing people with multiple sclerosis (PwMS) without depression or anxiety, according to a recent study. This study included 122 PwMS (75 women) divided into 4 subgroups according to their manifestation of depression and anxiety assessed by the Hospital Anxiety and Depression Scale (HADS) (ie, no depression/no anxiety, depression/no anxiety, no depression/anxiety, and depression/anxiety). Cognitive performance was evaluated via a computerized cognitive battery of tests. Participants were defined as “fallers” and “non-fallers” based on their fall history recorded during a clinical interview. Researchers found:
- 38 PwMS (31.1%) were classified as depressed (mean HADS 11.1, SD=3.4), 52 (42.6%) were classified as anxious (mean HADS 11.1, SD=3.1), and 56 (45.9%) were neither depressed nor anxious.
- PwMS categorized in the anxiety/non-depressed subgroup were 6 times less likely to fall than PwMS without depression or anxiety (OR=0.160).
- In terms of global cognitive status, depressed PwMS with anxiety were almost 4 times more likely to experience cognitive impairments compared to PwMS who were not depressed or anxious.
Kalron A, Aloni R, Allali G. The relationship between depression, anxiety and cognition and its paradoxical impact on falls in multiple sclerosis patients. [Published online ahead of print July 26, 2018], Mult Scler Relat Disord. doi:10.1016/j.msard.2018.07.029.
This Week's Must Reads
Cortical Dynamics in Essential Tremor Examined, Mov Disord; ePub 2018 Oct 21; Roy, et al
Distinguishing PD from PSP Through Biomarker, J Parkinsons Dis; 2018 Oct; Bottero, et al
Self-Reported Activity in Veterans with PD is Low, Parkinsonism Relat Disord; ePub 2018 Oct 23; Mantri, et al
End-Of-Life Experiences in Dementia with Lewy Bodies, J Am Geriatr Soc; ePub 2018 Oct 6; Armstrong, et al
First-Degree Kin of Patients with ET and Cognition, Parkinsonism Relat Disord; ePub 2018 Oct 30; Meyers, et al
Must Reads in Multiple Sclerosis
Link Between Fatigue and Fatigability Found in MS, Mult Scler Relat Disord; ePub 2018 Oct 27; Cehelyk, et al
How Patients with MS Use Various Coping Strategies, Mult Scler Relat Disord; ePub 2018 Oct 22; Holland, et al
Role of Family Planning in Women with MS, Front Neurol; ePub 2018 Oct 10; Kamm, et al
Urban Air Quality and Links to Pediatric MS, Ann Clin Transl Neurol; ePub 2018 Sep 27; Lavery, et al
DMT Cost Sharing Can Help Improve DMT Access in MS, Value Health; 2018 Sep; Shao, Stoecker, et al