Clinical Edge

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Increased risk of infection seen in patients with MS

Key clinical point: Multiple sclerosis is associated with increased risk for infection, including renal tract infection and hospitalized infections.

Major finding: The incidence rate of any infection was higher among patients with multiple sclerosis, compared with non–multiple sclerosis patients (4,805 vs. 2,731 per 10,000 person-years; incidence rate ratio, 1.76).

Study details: A study of 8,695 patients with multiple sclerosis and 86,934 matched patients without multiple sclerosis in a Department of Defense database.

Disclosures: The study was funded by a grant from Celgene, a subsidiary of Bristol-Myers Squibb. Four authors are employees of Bristol-Myers Squibb, and one author works for a company that does business with Celgene.


Jick S et al. ACTRIMS Forum 2020, Abstract P086.