Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Impact of Sleep Disorders on Patients with MS

Int J MS Care; ePub 2018 Jun 25; White, et al

The presence of a diagnosed sleep disorder may negatively impact health-related quality of life (HRQoL) in persons with multiple sclerosis (MS), a recent study found. Therefore, providers should continue to screen for sleep disorders, given their negative impact in patients with MS and the availability of effective treatments for both insomnia and obstructive sleep apneas (OSA). Researchers conducted a retrospective chart review of 531 patients with MS; 287 (54%) of whom also had a comorbid sleep disorder (either insomnia or OSA) while the remaining 244 (46%) participants did not have a diagnosed sleep disorder. They found:

  • Neither (1) average ratings of depression or HRQOL nor (2) the proportion of moderate depression or moderately impaired HRQoL differed between individuals with MS+insomnia and MS+OSA.
  • Neither sleep disorder predicted increased depression or poorer HRQoL.
  • However, individuals with a comorbid sleep disorder (MS+insomnia or MS+OSA) had poorer HRQoL compared to those without a diagnosed sleep disorder (MS only).
Citation:

White EK, Sullivan AB, Drerup M, from the Mellen Center for Multiple Sclerosis, Cleveland Clinic Foundation. Impact of sleep disorders on depression and patient-perceived health-related quality of life in multiple sclerosis. [Published online ahead of print June 25, 2018]. Int J MS Care. doi:10.7224/1537-2073.2017-068.

This Week's Must Reads

Cortical Dynamics in Essential Tremor Examined, Mov Disord; ePub 2018 Oct 21; Roy, et al

Distinguishing PD from PSP Through Biomarker, J Parkinsons Dis; 2018 Oct; Bottero, et al

Self-Reported Activity in Veterans with PD is Low, Parkinsonism Relat Disord; ePub 2018 Oct 23; Mantri, et al

End-Of-Life Experiences in Dementia with Lewy Bodies, J Am Geriatr Soc; ePub 2018 Oct 6; Armstrong, et al

First-Degree Kin of Patients with ET and Cognition, Parkinsonism Relat Disord; ePub 2018 Oct 30; Meyers, et al

Must Reads in Multiple Sclerosis

Link Between Fatigue and Fatigability Found in MS, Mult Scler Relat Disord; ePub 2018 Oct 27; Cehelyk, et al

How Patients with MS Use Various Coping Strategies, Mult Scler Relat Disord; ePub 2018 Oct 22; Holland, et al

Role of Family Planning in Women with MS, Front Neurol; ePub 2018 Oct 10; Kamm, et al

Urban Air Quality and Links to Pediatric MS, Ann Clin Transl Neurol; ePub 2018 Sep 27; Lavery, et al

DMT Cost Sharing Can Help Improve DMT Access in MS, Value Health; 2018 Sep; Shao, Stoecker, et al