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Arm Function Included in MS Short Form Questionnaire

Mult Scler; ePub 2018 Nov 9; Luijten, Eekhout, et al

Assessing arm and hand function of persons with multiple sclerosis (MS) is important as impaired functioning may impact daily activities and reduce quality of life. This according to a recent study that aimed to create a short form of the Arm Function in Multiple Sclerosis Questionnaire (AMSQ), a recently developed patient-reported outcome measure containing 31 items. Complete data from 690 patients with MS were included. A graded response model was fit to these data to estimate item response theory (IRT) parameters, which were used to perform post hoc computerized adaptive test (CAT) simulations with a cutoff standard error of measurement (SEM) of 0.32. Researchers found:

  • 10 items were selected for inclusion in the short form of the AMSQ based on 5 selection criteria (ie, discrimination parameters, total information, times selected in CAT simulations, raw item means, and item content).
  • The score on the final 10-item short form correlated strongly with the full-length AMSQ and provided reliable ability estimations, indicating its usefulness instrument in research and clinical settings.
Citation:

Luijten MAJ, Eekhout I, D’Hooghe M, Uitdehaag BMJ, Mokkink LB. Development of the arm function in multiple sclerosis questionnaire-short form (AMSQ-SF): A static 10-item version. [Published online ahead of print November 9, 2018]. Mult Scler. doi:10.1177%2F1352458518808197.Cost