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Arm Function Included in MS Short Form Questionnaire

Mult Scler; ePub 2018 Nov 9; Luijten, Eekhout, et al

Assessing arm and hand function of persons with multiple sclerosis (MS) is important as impaired functioning may impact daily activities and reduce quality of life. This according to a recent study that aimed to create a short form of the Arm Function in Multiple Sclerosis Questionnaire (AMSQ), a recently developed patient-reported outcome measure containing 31 items. Complete data from 690 patients with MS were included. A graded response model was fit to these data to estimate item response theory (IRT) parameters, which were used to perform post hoc computerized adaptive test (CAT) simulations with a cutoff standard error of measurement (SEM) of 0.32. Researchers found:

  • 10 items were selected for inclusion in the short form of the AMSQ based on 5 selection criteria (ie, discrimination parameters, total information, times selected in CAT simulations, raw item means, and item content).
  • The score on the final 10-item short form correlated strongly with the full-length AMSQ and provided reliable ability estimations, indicating its usefulness instrument in research and clinical settings.

Luijten MAJ, Eekhout I, D’Hooghe M, Uitdehaag BMJ, Mokkink LB. Development of the arm function in multiple sclerosis questionnaire-short form (AMSQ-SF): A static 10-item version. [Published online ahead of print November 9, 2018]. Mult Scler. doi:10.1177%2F1352458518808197.Cost