Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Restless Legs Syndrome Burdens Patients, Partners

Sleep Med; 2018 Jul; Ondo

Despite treatment, restless legs syndrome (RLS) continues to impact both subjects and their partners, according to a recent study. Therefore, impact on the partner/family should also be considered in clinical decision-making. In this study, the Patient Odyssey survey was commissioned by the Restless Legs Syndrome Foundation and designed to assess the day-to-day impact of RLS on patients and their spouses/partners. Researchers found:

  • Surveys were completed by 1,622 adult patients (70% female), and 676 adult spouses/partners (65% men and 35% women), either online or by mail.
  • RLS markedly impacted patient sleep as well as mitigated travel, work, and mood.
  • Patients reported significant problems with social aspects, sleep problems, and perceived lack of effective treatments and concern for their problems.
  • Partners also reported impact on their sleep, leisure time, and their relationship with the patient with RLS.


Ondo W. Restless legs syndrome “Patient Odyssey” survey of disease burden on patient and spouses/partners. Sleep Med. 2018;47:51-53. doi:10.1016/j.sleep.2017.12.003.

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