Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Patients with PD Having Lumbar Surgery: Greater LOS

Parkinsons Dis; ePub 2018 Jun 27; Steinberger, et al

Parkinson disease (PD) patients undergoing lumbar surgery for degenerative conditions have increased length of stay (LOS) and costs when compared to patients without PD, according to a recent study. Researchers examined the Nationwide Inpatient Sample from 2002 to 2011. Patients were included for study based on ICD-9-CM procedural codes for lumbar spine surgery and substratified to degenerative diagnoses. Incidence and baseline patient characteristics were determined. Multivariable analysis was performed to determine independent risk factors increasing incidence of lumbar fusion revision in PD patients. They found:

  • PD patients account for 0.9% of all degenerative lumbar procedures.
  • At baseline, PD patients are older (70.7 vs 58.9) and more likely to be male (58.6% male).
  • Mean LOS was increased in PD patients undergoing lumbar fusion (5.1 days vs 4.0 days) and lumbar fusion revision (6.2 days vs 4.8 days).
  • Costs were 7.9% higher for lumbar fusion and 25.2% higher for lumbar fusion revision in PD patients.
  • Multivariable analysis indicates that osteoporosis, fluid/electrolyte disorders, blood loss anemia, and insurance status are significant independent predictors of lumbar fusion revision in patients with PD.

Steinberger J, Gilligan J, Skovrlj B, et al. The effect of Parkinson’s disease on patients undergoing lumbar spine surgery. [Published online ahead of print June 27, 2018]. Parkinsons Dis. doi:10.1155/2018/8428403.

This Week's Must Reads

Fully Automated Test Gauges Processing Speed in MS, MS Mult Scler; ePub 2018 Aug 6; Patel, Shen, et al

Inflammation and Disability in Progressive-Onset MS, JAMA Neurology; ePub 2018 Aug 6; Hughes, et al

Mental Health’s Impact on Falls in Patients with MS, Mult Scler Relat Disord; ePub 2018 Jul 26; Kalron, et al

House-Call-Based Practice Viable for Advanced MS, Int J MS Care; ePub 2018 Aug 7; Healey, Zabad, et al

Detection of Chronic Active MS Lesions on 3T MRI, AJNR Am J Neuroradiol; 2018 Jul; Absinta, et al

Must Reads in Movement Disorders

Index Finger Pointing Observed in Movement Disorders, Front Neurol; ePub 2018 Jul 4; Vives-Rodriguez, et al

Contact Sports Linked with Lewy Body Pathology, J Neuropathol Exp Neurol; ePub 2018 Jul 25; Adams, et al

Predictors of Worsening HRQL in Parkinson Disease, Parkinsonism Relat Disord; ePub 2018 Jul 2; Margolius, et al

Patients with PD Having Lumbar Surgery: Greater LOS, Parkinsons Dis; ePub 2018 Jun 27; Steinberger, et al

DBS Surgery with General Anesthesia Safe, Effective , J Neurosurg; 2018 Aug; Chen, Mirzadeh, Chapple, et al