Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Freezing of Gait and Foot Strike Variability PD

Parkinsonism Relat Disord; ePub 2018 May 1; Shah, et al

Parkinson disease (PD) subjects with freezing gait (FOG) had increased variability in foot strike suggesting that in addition to stride length variability, foot strike variability could contribute to imbalance leading to falls. This according to a recent study that evaluated whether there was an objective gait correlate to the increased stumbling reported by many patients with gait freezing. 72 age-matched subjects (22 PD FOG, 27 PD no-FOG, and 23 healthy controls [HC]) were enrolled. Subjects with >1 fall/day or a Montreal Cognitive Assessment score <10 were excluded. Subjects walked at their normal pace, 8 lengths of a 20 × 4 foot pressure-sensor mat. Researchers found:

  • Foot strike variability could contribute to imbalance leading to falls.
  • Mean dimensions of foot strike were not significantly different between groups, but PD FOG subjects had increased step-to-step variability in foot strike as measured by the percent coefficient of variation (%CV) in foot strike length compared to PD no-FOG and HC, independent of stride velocity.
  • In PD no-FOG subjects, fallers also had higher variability in foot strike length compared to non-fallers.
Citation:

Shah J, Pillai L, Williams DK, et al. Increased foot strike variability in Parkinson's disease patients with freezing of gait. [Published online ahead of print May 1, 2018]. Parkinsonism Relat Disord. doi:10.1016/j.parkreldis.2018.04.032.

This Week's Must Reads

PD Global Burden More than Doubles, from 1990-2016, Lancet Neurol; ePub 2018 Oct 1; Dorsey, et al

Disparities Found in Dementia Medication Use for PD, JAMA Neurol, ePub 2018 Oct 1; Mantri, Fullard, et al

Gray Matter Abnormalities in Movement Disorders, Neurology; ePub 2018 Oct 10; Maurer, LaFaver, et al

Periodic Limb Movements in Sleep Increase with Age, Clin Neurophysiol; 2018 Nov; Leary, Moore IV, et al

Cognitive Ability Assessment Tool Proves Effective, Mov Disord; ePub 2018 Oct 10; Holden, Medina, et al

Must Reads in Movement Disorders

PD Global Burden More than Doubles, from 1990-2016, Lancet Neurol; ePub 2018 Oct 1; Dorsey, et al

Disparities Found in Dementia Medication Use for PD, JAMA Neurol, ePub 2018 Oct 1; Mantri, Fullard, et al

Gray Matter Abnormalities in Movement Disorders, Neurology; ePub 2018 Oct 10; Maurer, LaFaver, et al

Periodic Limb Movements in Sleep Increase with Age, Clin Neurophysiol; 2018 Nov; Leary, Moore IV, et al

Cognitive Ability Assessment Tool Proves Effective, Mov Disord; ePub 2018 Oct 10; Holden, Medina, et al