Parkinson disease (PD) subjects with freezing gait (FOG) had increased variability in foot strike suggesting that in addition to stride length variability, foot strike variability could contribute to imbalance leading to falls. This according to a recent study that evaluated whether there was an objective gait correlate to the increased stumbling reported by many patients with gait freezing. 72 age-matched subjects (22 PD FOG, 27 PD no-FOG, and 23 healthy controls [HC]) were enrolled. Subjects with >1 fall/day or a Montreal Cognitive Assessment score <10 were excluded. Subjects walked at their normal pace, 8 lengths of a 20 × 4 foot pressure-sensor mat. Researchers found:
- Foot strike variability could contribute to imbalance leading to falls.
- Mean dimensions of foot strike were not significantly different between groups, but PD FOG subjects had increased step-to-step variability in foot strike as measured by the percent coefficient of variation (%CV) in foot strike length compared to PD no-FOG and HC, independent of stride velocity.
- In PD no-FOG subjects, fallers also had higher variability in foot strike length compared to non-fallers.
Shah J, Pillai L, Williams DK, et al. Increased foot strike variability in Parkinson's disease patients with freezing of gait. [Published online ahead of print May 1, 2018]. Parkinsonism Relat Disord. doi:10.1016/j.parkreldis.2018.04.032.
This Week's Must Reads
TBI Linked with 2-fold Increase Risk of Dementia, JAMA Neurology; ePub 2018 May 7; Barnes, et al
APOE ε2ε4 Genotype Linked with Cognitive Impairment, Neurology; ePub 2018 May 11; Oveisgharan, et al
Depressive Symptoms, Memory, and the Aging Brain , Neurology; ePub 2018 May 9; Al Hazzouri, et al
Patient Satisfaction with Sleep Study Experience, Sleep; ePub 2018 May 8; Kapur, Johnston, et al
More Severe Seizure Patterns Favor Daytime, Epilepsia; ePub 2018 Apr 23; Goldenholz, et al
Must Reads in Movement Disorders
Demoralization in PD Linked to Motor Dysfunction, Neurology; 2018 May; Koo, Chow, Shah, et al
Susceptibility MRI Reveals PD Progression Patterns, Mov Disord; ePub 2018 May 14; Du, Lewis, et al
Autonomic Dysfunction Symptoms in Patients with PD, Neurology; ePub 2018 May 4; Dayan, Sklerov, et al
Freezing of Gait and Foot Strike Variability PD, Parkinsonism Relat Disord; ePub 2018 May 1; Shah, et al
Baseline Markers of Future Psychosis in Early PD, Neurology; 2018 May; Barrett, Blair, et al