The prevalence of antipsychotic use in patients with Parkinson disease (PD) is lower than expected from previously reported cumulative incidences, according to a recent study. Dementia is highly prevalent in those starting antipsychotics and most of the patients on antipsychotics had a reasonable risk-benefit ratio for taking them. Researchers used the medical records-linkage system of the Rochester Epidemiology Project to study the use of antipsychotic medication in all persons with PD (n=296) in Olmsted County, MN, on January 1, 2006. They found:
- The overall prevalence of antipsychotic use was 9.8% (29 of 296); 95.5% (28 of 29) of the patients had dementia when initiating antipsychotics.
- The most frequent indication (71.4%; 20 of 28) was psychosis or behavior threatening to the patient or others.
Bower JH, Grossardt BR, Rocca WA, Savica R. Prevalence of and indications for antipsychotic use in Parkinson's disease. [Published online ahead of print December 26, 2017]. Mov Disord. doi:10.1002/mds.27256.
This Week's Must Reads
Recurrent Stroke Risk Higher for Blacks than Whites, Neurology; ePub 2018 Oct 3; Albright, Huang, et al
Sleep Duration/Stroke Link Differs by Race and Sex, Neurology; ePub 2018 Oct 3; Petrov, Howard, et al
Intracerebral Hemorrhage Survivors’ Outcomes Studied, J Stroke Cerebrovasc Dis; ePub 2018 Sep 28; Griauzde, et al
Probable OSA Common in Refractory Epilepsy, Epilepsia; ePub 2018 Sep 24; McCarter, et al
FDA Approves Tiglutik for Treatment of ALS, ITF Pharma news release; 2018 Sep 6
Must Reads in Movement Disorders
Is RLS Associated with Premotor Symptoms of PD?, J Neurol Sci; ePub 2018 Sep 1; Iwaki, Hughes, et al
Cognition Function and Increased Risk for PD, PLoS One; ePub 2018 Aug 20; Chahine, et al
Comparison of Tests for Cognitive Deficits in PD, Mov Disord; ePub 2018 Sep 14; Hoogland, et al
Spiral Drawings in ET Measure Motor Learning, Cerebellum; ePub 2018 Sep 11; Kim, Luo, et al
Appendectomy and Risk of Parkinson Disease, Mov Disord; ePub 2018 Sep 14; Palacios, et al