Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Study Delineates Spectrum of Dravet Syndrome Phenotypes

Key clinical point: Initial presentations of Dravet syndrome often differ from the prototypical phenotype.

Major finding: About half of patients (46%) have an afebrile seizure as their first seizure, and it is common for patients to present with seizures before age 5 months.

Study details: An analysis of the clinical histories of 188 patients with Dravet syndrome and pathogenic SCN1A variants.

Disclosures: The researchers had no disclosures.

Citation:

Li W et al. AES 2019. Abstract 2.116.