Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Nimodipine Does Not Improve Subarachnoid Hemorrhage Outcomes

Publish date:: April 30, 2019

Key clinical point: EG-1962 is no more effective than oral nimodipine in patients with aneurysmal subarachnoid hemorrhage.

Major finding: The proportion of patients with a favorable outcome on the extended Glasgow Outcome Scale was 46% in the EG-1962 arm and 43% in the comparator group.

Study details: A randomized, double-blind, placebo-controlled, international phase 3 trial that included 282 participants.

Disclosures: Several investigators are employees of Edge Therapeutics, which developed EG-1962.

Citation:

Mayer SA et al. ISC 2019, Abstract LB15.

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