Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Dietary Fiber, CRP & Physical Activity Evaluated

Metab Syndr Relat Disord; ePub 2018 Jan 29; Richardson, et al

Waist circumference (WC) and standing height may mediate the beneficial association between increased fiber intake and lower odds of elevated C-reactive protein (CRP) in adults reporting leisure-time physical activity (LTPA) participation, a recent study found. A sample (n=8372) adults (aged ≥20 years) participated in the 2007–2010 National Health and Nutrition Examination Survey. Tertiles of reported fiber intake were created. The dependent variable was elevated CRP (>3–10 mg/L). Researchers found:

  • In adults reporting any volume of LTPA participation, increased fiber intake was significantly associated with lower odds of having an elevated CRP concentration when compared with the lowest tertile.
  • Similar associations were not revealed in analyses limited to adults reporting no LTPA participation.
  • After additional adjustment for WC and standing height, this protective association was no longer statistically significant.


Richardson MR, Arikawa AY, Churilla JR. Dietary fiber, C-reactive protein, and leisure-time physical activity among U.S. adults. [Published online ahead of print January 29, 2018]. Metab Syndr Relat Disord. doi:10.1089/met.2017.0100.

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