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T2D Continuous Care Model Compared to Usual Care

Diabetes Ther; ePub 2018 Feb 7; Hallberg, et al

People with diabetes who received metabolic and continuous remote care experienced improvements in HbA1C, weight, and other biomarkers, according to an open-label, non-randomized, controlled, before-and-after 1-year study involving 349 individuals. They were also able to reduce medication use. Participants received either the continuous care intervention (CCI; n=262) or usual care (n=87). Investigators looked at HbA1C, weight, medication use, fasting serum glucose and insulin, HOMA-IR, blood lipids and lipoproteins, liver and kidney function markers, and high-sensitivity C-reactive protein (hsCRP). In the 83% of patients in the CCI group who remained in the intervention at 1 year:

  • HbA1C declined from 7.6% to 6.3%.
  • Weight declined 13.8 kg.
  • Diabetes prescriptions other than metformin declined from 57% to 30%.
  • Insulin therapy was reduced/eliminated in 94%.
  • Sulfonylureas were eliminated in all.
  • HOMA-IR and hsCRP declined 55% and 39%, respectively.
  • Triglycerides declined 24%.
  • HDL- and LDL-cholesterol increased 18% and 10%, respectively.
  • Serum creatinine and liver enzymes declined.

Patients receiving usual care had no changes in biomarkers or diabetes prescriptions.

Citation:

Hallberg S, McKenzie A, Williams P, et al. Effectiveness and safety of a novel care model for the management of type 2 diabetes at 1 year: An open-label, non-randomized, controlled study. [Published online ahead of print February 7, 2018]. Diabetes Ther. doi:10.1007/s13300-018-0373-9.

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