Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Patient Characteristics Linked with Hypoglycemia

Diabetes Care; ePub 2018 Mar 16; Misra-Hebert, et al

In a recent, retrospective, cohort study of patients with type 2 diabetes with severe hypoglycemia, high-risk patient characteristics were identified. For example, patients with severe hypoglycemia had previous non-severe hypoglycemia diagnoses more frequently than those without. Therefore, identifying patients at high risk at the point of care can allow for change in modifiable risk factors and prevention of severe hypoglycemia events. From January 2006 to December 2015, researchers used electronic medical records in the Cleveland Clinic Health System (CCHS). Participants included 50,439 patients with type 2 diabetes receiving care in the CCHS. Number of severe hypoglycemia events and associated patient characteristics were identified. They found:

  • The incidence proportion of severe hypoglycemia increased from 0.12% in 2006 to 0.31% in 2015.
  • Compared with patients who did not experience severe hypoglycemia, those with severe hypoglycemia had similar median glycosylated hemoglobin (HbA1c) levels.
  • More patients with severe hypoglycemia vs those without had a prior diagnosis of non-severe hypoglycemia (9% vs 2%).
Citation:

Misra-Hebert AD, Pantalone KM, Ji X, et al. Patient characteristics associated with severe hypoglycemia in a type 2 diabetes cohort in a large, integrated health care system from 2006 to 2015. [Published online ahead of print March 16, 2018]. Diabetes Care. doi:10.2337/dc17-1834.

This Week's Must Reads

Clinical Guideline Update for Testosterone Therapy , J Clin Endocrinol Metab; ePub 2018 Mar 17; Bhasin, et al

Patient Characteristics Linked with Hypoglycemia, Diabetes Care; ePub 2018 Mar 16; Misra-Hebert, et al

Food Insecurity, Poor Access, and Glycemic Control, Diabetes Care; ePub 2018 Mar 19; Berkowitz, et al

Chronic Stress, Risk Taking, and Visceral Fat, Obesity; ePub 2018 Mar 22; Mason, et al

Obesity Progression and Incident Diabetes Examined, Diabetes Care; ePub 2018 Mar 5; Stokes, Collins, et al

Must Reads in Diabetes

Patient Characteristics Linked with Hypoglycemia, Diabetes Care; ePub 2018 Mar 16; Misra-Hebert, et al

Food Insecurity, Poor Access, and Glycemic Control, Diabetes Care; ePub 2018 Mar 19; Berkowitz, et al

Obesity Progression and Incident Diabetes Examined, Diabetes Care; ePub 2018 Mar 5; Stokes, Collins, et al

CV and Renal Burdens of Prediabetes in the US, Lancet Diabetes Endocrinol; ePub 2018 Feb 27; Ali, et al

Retinal Changes and Cognitive Decline in T1D, Diab Vasc Dis Res; ePub 2018 Feb 28; Nunley, et al