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Burden of Diabetic Ketoacidosis Over Past Decade

Diabetes Care; ePub 2018 May 17; Desai, et al

The population incidence for diabetic ketoacidosis (DKA) hospitalizations in the US continues to increase, but the mortality of this condition has significantly decreased, indicating advances in early diagnosis and better inpatient care, a recent study found. Researchers reviewed the National Inpatient Sample Database for all hospitalizations in which DKA was the principal discharge diagnosis during 2003–2014 and calculated the population incidence by using US census data. Patients with codes for diabetic coma were excluded because the codes do not distinguish between hypoglycemic and DKA-related coma. They found:

  • There were 1,760,101 primary admissions for DKA during the study period.
  • In-hospital mortality for the cohort was 0.4% (n=7,031).
  • The total number of hospital discharges with the principal diagnosis of DKA increased from 118,808 in 2003 to 188,965 in 2014.
  • The resulting aggregate charges (ie, national bill) for diabetes with ketoacidosis increased dramatically from $2.2 billion (after adjusting for inflation) in 2003 to $ 5.1 billion in 2014.
  • However, there was a significant reduction in mortality from 611 (0.51%) in 2003 to 620 (0.3%) in 2014.

Citation:

Desai D, Mehta D, Mathias P, Menon G, Schubart UK. Health care utilization and burden of diabetic ketoacidosis in the U.S. over the past decade: A nationwide analysis. [Published online ahead of print May 17, 2018]. Diabetes Care. doi:10.2337/dc17-1379.

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