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Study identifies risk factors for infection after transbronchial biopsy

Key clinical point: Among patients who undergo endobronchial ultrasound-guided transbronchial biopsy using a guide sheath (EBUS-GS-TBB) for diagnosing lung cancer, cavitation and low-density areas inside the target lesion on CT and stenosis of the responsible bronchus are risk factors for infection after the procedure.

Major finding: On multivariate analysis, cavitation in the lesion (odds ratio, 3.63), low-density areas in the lesion (OR, 13.26), and bronchoscopic findings of responsible bronchus stenosis (OR, 7.82) were significantly associated with development of infections post biopsy.

Study details: A retrospective study of 1,045 patients who underwent EBUS-GS-TBB at a hospital in Japan.

Disclosures: The researchers had no disclosures.


Souma T et al. CHEST. 2020 Mar 4. doi: 10.1016/j.chest.2020.02.025.