Clinical Edge

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AI algorithm predicts treatment success in lung cancer patients

Key clinical point: An artificial intelligence–derived algorithm predicted success for three non–small cell lung cancer therapies.

Major finding: The prediction models for nivolumab, docetaxel, and gefitinib yielded area under the curve results of 0.77, 0.67, and 0.82, respectively.

Study details: A retrospective analysis of data from clinical trials of 188 patients with non–small cell lung cancer.

Disclosures: The study was supported by Bristol-Myers Squibb, the National Institutes of Health, Fondation Philanthropia, and Fondation Nuovo-Soldati. The authors disclosed relationships, including employment, with Bristol-Myers Squibb. They also disclosed relationships with Roche, Novartis, Merck, and Boehringer Ingelheim.


Dercle L et al. Clin Cancer Res. 2020 Mar 20. doi: 10.1158/1078-0432.CCR-19-2942.