Key clinical point: Blood eosinophil count (BEC), a "treatable trait" in asthma, works differently in chronic obstructive pulmonary disease (COPD).
Major finding: Genes and pathways connected to BEC typically don't share genes and pathways in both asthma and COPD.
Study details: Molecular analysis of 368 patients with asthma or COPD.
Disclosures: The Airway Disease Predicting Outcomes through Patient Specific Computational Modeling project (with various funders) and Wellcome Trust and National Institute for Health Research Leicester Respiratory Biomedical Center funded the study. The authors report no disclosures.
George L et al. Allergy. 2019 Sep 10.