Clinical Edge

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COPD and Angiographically Diagnosed CAD

COPD: J Chron Obstr Pulm Dis; ePub 2019 Mar 22; Hong, et al

In patients undergoing coronary angiography, chronic obstructive pulmonary disease (COPD) was negatively associated with coronary artery disease (CAD), with and without adjustment for risk factors, a new study found. Adult patients who had undergone coronary angiogram between April 1, 2007 and March 31, 2014 in Alberta, Canada were included. Researchers evaluated the association between COPD and CAD using univariable and multivariable logistic regression. They found:

  • 26,137 patients (mean age 63.3 years, 74.8% male) were included.
  • The crude odds ratio (OR) of having CAD was 0.83 for patients with COPD vs those without COPD.
  • The adjusted OR was 0.75 after controlling for age, sex, smoking history, body mass index, hypertension, diabetes, hyperlipidemia, peripheral artery disease and cardiac family history.


Hong Y, Graham MM, Southern D, McMurtry MS. The association between chronic obstructive pulmonary disease and coronary artery disease in patients undergoing coronary angiography. [Published online ahead of print March 22, 2019]. COPD: J Chron Obstr Pulm Dis. doi:10.1080/15412555.2019.1566894.