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CAP Burden in Patients with COPD

Chronic Obstr Pulm Dis; ePub 2019 Mar; Pasquale, et al

Community-acquired pneumonia (CAP) is a burdensome condition in patients with chronic obstructive pulmonary disease (COPD), a condition that can impair activities for weeks and include lingering symptoms. This according to a new study that examined CAP burden from a COPD patient perspective. Patients completed the CAP Burden of Illness Questionnaire (CAP-BIQ), a content validated questionnaire assessing CAP symptomology, duration of symptoms, and CAP impact on work, activities, and family, at baseline and at 30 days follow-up. Among the details:

  • 481 patients had sufficient data for analysis.
  • The prevalence of respiratory-related symptoms was very high (>90%) at the time of diagnosis with other generalized symptoms such as fatigue, trouble sleeping, headaches, and confusion present in >60% of participants.
  • Mean duration of symptoms varied from ~2 weeks for headaches and fever to more than a month for fatigue, wheezing, dyspnea, and cough.
  • Employed participants missed an average of 21 days of work.
  • 84% of patients required help from family, friends, or caregivers.


Pasquale CB, Vietri J, Choate R, et al. Patient-reported consequences of community-acquired pneumonia in patients with chronic obstructive pulmonary disease. Chronic Obstr Pulm Dis. 2019;6(2): In press. doi:10.15326/jcopdf.6.2.2018.0144.