Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Airflow Obstruction and Comorbidities in COPD

The role of common risk factors may help explain the coexistence of cardio-metabolic comorbidities and chronic obstructive pulmonary disease (COPD), a new study found. Researchers assessed the association between airflow obstruction and cardiovascular disease (CVD), hypertension, and diabetes. They found:

  • 23,623 participants (47.5% male, 19.0% current smokers, median age 55.1 years) were included.
  • 10.4% of participants had airflow obstruction.
  • After adjustment, odds ratios for the association with airflow obstruction were 1.00 for CVD, 1.14 for hypertension, and 0.76 for diabetes with similar results for men and women, smokers and nonsmokers, in richer and poorer centers.


Triest FJJ, et al. Airflow obstruction and cardio-metabolic comorbidities. [Published online ahead of print May 27, 2019]. COPD. doi: 10.1080/15412555.2019.1614550.