Clinical Edge

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TAVR for bicuspid aortic stenosis gets selective thumbs up

Key clinical point: TAVR is now a reasonable option for patients with bicuspid AS who are at intermediate or high surgical risk.

Major finding: The 1-year all-cause mortality rates were 10.8% in patients who underwent TAVR for bicuspid AS and similar at 12.1% following TAVR for tricuspid AS.

Study details: This was a study of outcomes in 2,691 patients in the STS/ACC Transcatheter Valve Therapy Registry who underwent TAVR for bicuspid AS and an equal number of propensity-matched patients who had TAVR for tricuspid AS.

Disclosures: The study was supported by Edwards Lifesciences. The presenter reported receiving research grants from and serving as a consultant to that company and several other medical device makers.


Makkar RR. ACC 19, 404-15. Late breaking clinical trials