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Prevalence of Fatigue in Patients with Asthma

J Clin Med; ePub 2018 Nov 23; Van Herck, et al

Severe fatigue is highly prevalent in patients with asthma and moderately associated with dyspnea, asthma control, and asthma-related quality of life (QOL), a new study found. The retrospective cross-sectional study of outpatients with asthma upon referral to a chest physician assessed fatigue, lung function, asthma control, exercise capacity, and asthma-related QOL. Researchers found:

  • 733 patients with asthma (mean age 47.4 ±16.3 years, 41% male) were eligible and analyzed.
  • Severe fatigue was detected in 62.6% of patients.
  • Fatigue was not related to airflow limitation but was moderately related to asthma control, asthma-related QOL, and dyspnea.
  • In stepwise multiple regression analysis, 28.9% of variance in fatigue was explained by asthma control, dyspnea, and age.


Van Herck M, Spruit MA, Burtin C, et al. Fatigue is highly prevalent in patients with asthma and contributes to the burden of disease. [Published online ahead of print November 23, 2018]. J Clin Med. doi:10.3390/jcm7120471.