Perioperative blood transfusion and survival of breast cancer patients after modified radical mastectomy
Nan Yuh Hoe, MBBS
Kryzysztoff J. Herman, MD
Robert E Hermann, MDAddress reprint requests to R.E.H., Department of General Surgery, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195.
Sharon V. Medendorp, MPH
To investigate the effect of perioperative blood transfusion on the survival of patients with breast cancer, the authors reviewed the clinical records of 455 patients who underwent modified radical mastectomy between 1960 and 1979. Thirty-eight patients (8.4%) received blood transfusions. For stage I patients who received perioperative transfusions, 5- and 10-year survival rates were 5 3 % and 47%; for the no-transfusion group, the rates were 9 3 % and 85%. There was also a significant difference in disease-free survival for stage I patients: for the transfusion group, 5- and 10-year survival rates were 47%; for the group not receiving a transfusion, the rates were 8 9 % and 84%. For stage II patients, there was no difference in total or disease-free survival between those who received transfusions and those who did not, and both groups had comparable distribution of nodes.