Monocytic leukemoid reaction, glucocorticoid therapy, and myelodysplastic syndrome
Manoel Moraes, MD
John Wilkes, MD
James N. Lowder, MDAddress reprint requests to J.N.L., Becton Dickinson Advanced Diagnostics, 225 International Circle, Cockeysville, Maryland 21030.
A leukemoid reaction is a complex and poorly understood response by the bone marrow to a variety of stresses; although any peripheral blood cell line may be involved, it is rarely a purely monocytic event. A case is reported of a true monocytic leukemoid reaction in a patient with myelodysplastic syndrome related to the effect of corticosteroids on the underlying marrow disorder.