Assessment of the size of acute myocardial infarction I: biochemical methods
Albert V. G. Bruschke, MDAddress reprint requests to A.V.G.B., Department of Cardiology, University Hospital, Rijnsburgerweg 10, 2333 AA Leiden, the Netherlands.
Arnoud van der Laarse, PhD
Ernst E. van der Wall, MD
Determination of infarction size is essential to evaluate interventions designed to salvage myocardium.Properly executed enzyme methods probably have the highest accuracy but can only be used in the early stage of infarction. Measurement of slowly catabolized enzymes such as LDH, LDH-1, and alpha-HBDH is recommended for routine purposes.