Carbamazepine-induced dyskinesia and ophthalmoplegia
Michael J. Schwartzman, DOAddress reprint requests to M.J.S., Neuromuscular Program, Department of Neurology, Cleveland Clinic Foundation, One Clinic Center, 9500 Euclid Avenue, Cleveland, Ohio 44195.
Ilo E. Leppik, MD
Antiepileptic drug-induced dyskinesias are well described with phenytoin but have only occasionally been reported with carbamazepine. We present two patients with carbamazepine-induced dyskinesia, one with ocular skew deviation and down-beating nystagmus associated with a high therapeutic level, and another with systemic dyskinesia with a toxic carbamazepine level, and compare these with previously reported cases.