Thrombotic thrombocytopenic purpura in a patient with AIDS
Glenn H. Segal, DOAddress reprint requests to G.H.S., Department of Pathology, The Cleveland Clinic Foundation, One Clinic Center, 9500 Euclid Avenue, Cleveland, Ohio 44195.
Raymond R. Tubbs, DO
Norman B. Ratliff, MD
Michael L. Miller, DO
David L. Longworth, MD
Thrombotic thrombocytopenic purpura (TTP) has only recently been documented in association with human immunodeficiency virus infection. The authors present the clinical, laboratory, and pathologic features of a unique case of secondary thrombotic thrombocytopenic purpura occurring in a patient with AIDS, including the immunohistologic characterization of the vascular thrombi. They also review 12 previously reported cases of thrombotic thrombocytopenic purpura associated with human immunodeficiency virus infection.