Secretory villous tumor of the ampulla of Vater1

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An unusual case of a malignant villous tumor of the ampulla of Vater is presented. This tumor caused a sodium- and chloride-rich secretion into the biliary tree. A percutaneous transhepatic drainage tube was inserted, and the resultant fluid loss caused hyponatremia, hypochloremia, and oliguric renal failure. Villous tumors of the ampulla may sometimes secrete large quantities of fluid in a manner analogous to rectal villous tumors.



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