Membrane plasmapheresis and the developing technology of plasma therapy1
James W. Smith, M.D., Ph.D.
Paul S. Malchesky, D.Eng.
Yukihiko Nosé, M.D., Ph.D.
Therapeutic plasmapheresis has been used increasingly in the treatment of a variety of diseases. Membrane plasma filters have been developed that produce a cell-free and particulate-free plasma ideally suited for on-line plasma treatment systems. Clinical experience with sorbent and filtration techniques for solute removal indicate promising directions for plasma therapy and its role in treating and understanding disease.