Scleromyxedema associated with IgG lambda multiple myeloma1

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Scleromyxedema (papular mucinosis) is a rare disorder characterized by proliferation of fibroblasts and cutaneous deposition of acid mucopolysaccharides, usually without disturbances of thyroid function. Associated abnormal proteins in the serum, identified as paraproteins, are a main feature of this disease. The association of scleromyxedema with classicial plasmacytoma or multiple myeloma is extremely rare. We report a case of scleromyxedema associated with multiple myeloma of the IgG lambda type.



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