Artificial Fever

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Hyperpyrexia by physical means is definitely established as a method for treating disease. At the present time physical agents may be utilized by various methods for this procedure. These are radiant heat, luminous heat cabinets, nonluminous heat cabinets, electric blankets, high frequency electrical currents, short wave diathermy, hydrotherapeutic methods, and hot water bottle and blanket method.

I do not wish to discuss the advantages or disadvantages of any of the above methods, but rather to review briefly the results that have been obtained by the use of these methods in the treatment of various pathological conditions.

Artificial fever is not new in the armamentarium of therapeutics, various substances having been used to produce fever in patients. Among the more common, the following may be mentioned: tuberculin, sterile milk, sodium nucleinate, typhoid vaccine, suspensions of sulphur in oil, relapsing fever, sodoku, and malaria. Inoculations with typhoid vaccine and malaria are very popular. However, after the original work of Neymann and Osborne1 in 1929 in the production of artificial fever with high frequency currents, a new field of investigation was begun and has had a very rapid development.

In a review of the literature for 1935, Krusen2 found that fever produced by physical means has been recommended for the treatment of no less than fifty different diseases. Results in the treatment of the majority of these diseases have not been encouraging, although for a selected group of patients this method has given promise of great usefulness. Neymann3 has studied very thoroughly and. . .



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