Malignant Argentaffinoma

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ALTHOUGH the occurrence of argentaffinoma in the pediatric age group has been well documented,1–3 it is an unusual tumor of childhood. Field, Adamson, and Stoeckle1 recently reviewed 19 reported cases of patients up to 16 years of age, and added a case of a functional tumor in a boy 15 years old. The majority of reported argentaffinomas in children have been isolated tumors of the appendix,2 discovered at the time of laparotomy for appendicitis. Childhood extra-appendiceal argentaffinomas have occurred in a Meckel’s diverticulum,3 as a single polypoid lesion of the stomach,4 and as ilial tumors producing intussusception.5 The case reported by Field, Adamson, and Stoeckle apparently is of the youngest patient in whom a preoperative diagnosis was made.

This report concerns a case of an extraappendiceal malignant argentaffinoma that developed in the ileum of a child aged 11 years.

Report of a Case

An 11-year-old white boy was first examined at the Cleveland Clinic Hospital in August, 1964, because of recurrent cramping abdominal pain of 11 months’ duration. Cramping discomfort had been episodic, lasting from 10 to 15 minutes, confined to the lower abdomen, and characteristically after meals. For several months his parents had noted nocturnal borborygmi. There had been no change in bowel habits.

In November, 1963, two months after the onset of the illness, and again one week before examination at the Cleveland Clinic, the patient was admitted to a hospital. At the time of the initial hospitalization, upper gastrointestinal and colon barium-contrast studies were performed and were . . .



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