Mucoepidermoid Carcinoma of Salivary Gland Origin

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MUCOEPIDERMOID CARCINOMA, a distinctive neoplasm of salivary gland origin, had received comparatively little consideration in the medical literature until recent years. It is the purpose of this report to review the features of this neoplasm as previously described and to present 12 additional cases.

The first authentic instance of mucoepidermoid carcinoma was reported by Schilling1 in 1921; the tumor arose in the parotid gland. However, there is some possibility that cases mentioned earlier by Volkmann2 and Lecene3 are examples of this tumor. In 1940, in addition to presenting eight cases of mucoepidermoid carcinoma, Skorpil4 reviewed the literature and found seven previously reported instances of the neoplasm. In this country, it was not until 1945 that Stewart, Foote and Becker5 first described this tumor and recognized it as an entity. In their report they analyzed the data derived from a study of 45 cases of this salivary gland neoplasm, for which they suggested the name mucoepidermoid tumor. In 1948 Lindell6 described 12 additional examples and presented a detailed analysis of the reported cases. In 1949 Godwin and Colvin7 described two more instances, in 1950 Rawson, Howard, Royster and Horn8 mentioned 12, and in 1951 Kirklin, McDonald, Harrington and New9 included 19 in a report of parotid tumors in general. Pung10 added one case in 1952, and in 1953 eight were described in a report by Bauer and Bauer11 and eight more were mentioned by Slaughter, Southwick and Walter.12 It will be noted that the majority of the case reports have been . . .



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