Resistant Cases of Meniere's Disease*

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MUCH has been written about Meniere's disease and its treatment since Meniere's initial classic description in 1861. Many theories and explanations have been offered in an attempt to clarify the problems involved. This fact alone signifies that a certain amount of confusion, with regard to the etiology and pathology as well as the treatment of the disease, has existed. It has mainly been in the past decade that writers such as Day1 have clarified the meaning of the term “Meniere's disease,” and differentiated between it and the pseudo-Meniere's disease, which Dandy used to label those cases which had only vestibular involvement.

The term Meniere's disease is reserved for that group of patients presenting the syndrome comprising vertigo, tinnitus, deafness and sometimes nausea and vomiting, for which no definite systemic or local condition can be blamed. Heretofore, many patients with dizziness and nausea or vomiting were diagnosed as having Meniere's disease even though there was no cochlear involvement. Meniere's syndrome, or components, may be caused by a variety of conditions but now, it is generally agreed, only the patients belonging to the idiopathic group warrant a diagnosis of Meniere's disease.


Investigators have attempted to prove the etiology of Meniere's disease for many years. Meniere's syndrome may have toxic origin such as poisoning from lead, arsenic in alcohol, mercury, salicylates, and other drugs. It is also present with chronic infections, the exanthemata, syphilis, tuberculosis, the anemias, leukemias, virus infections, purpuras, tumors of the cerebellopontine angle, trauma, and gastrointestinal conditions.2 Among the . . .



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