Brain Tumor in Infancy

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ALTHOUGH tumors of the brain are encountered with moderate frequency during childhood, their occurrence during the first year of life is distinctly rare. Stern1 found 62 intracranial tumors in children under the age of 12 at 2808 consecutive autopsies at the Great Ormond Hospital; of these, 6 occurred during the first year of life. Critchley2 reported 125 brain tumors in children under the age of 16 among a total of 1028 cases of brain tumor; only 1 of these occurred in an infant under the age of one year. Cushing,3 in a series of 1108 verified intracranial tumors, found 24 in children younger than 5 years; one of these proved to be a teratoma in an infant 2 months of age. Gross4 reviewed the literature concerning tumors of the brain during the first 2 years of life, citing 9 cases which had been reported from 1861 to 1931; to these he added 9 cases which he had observed in the same age group. In a series of 100 intracranial tumors occurring in children under 15 years of age, Smith and Fincher5 encountered none during the first year of life. In a review of the literature of cases of brain tumor occurring during the neonatal period (the first 60 days of life) Arnstein et al6 found 13 reports of such lesions prior to June 1950 and added a case of angioma of the choroid plexus in a 3 day old infant. Bailey et al7 in their complete monograph reviewed a series. . .



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