Skin Imprints in Cutaneous Lymphoblastoma

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BECAUSE of their accuracy, speed and simplicity in the diagnosis of cutaneous lymphoblastoma, tissue imprints deserve greater clinical application. Recently, 2 cases of lymphoblastoma of the lymphocytic type involving the skin alone have been diagnosed in the Department of Dermatology, and in each instance the tissue imprint provided specific and more rapid information than the routine pathologic preparation of the tissue from which the imprints were made. One of these cases is reported.

Case Report

A registered nurse, aged 59, was first seen in the Cleveland Clinic on December 29, 1948. She had been in good health until October 1, 1948, when she noted the onset of lumps in the skin of the right lateral thigh. Microscopic examination of one of these lumps was reported as panniculitis. Other indurations appeared gradually at other sites, eventually involving most of the body and face (fig. 1). The lumps were indurated and bluish to purple in color. There was occasional pruritus. In December 1948 she developed many red streaks and patches of erythema which were attributed to phenobarbital. Stopping the drug had no effect on the lesions. A moderate degree of ankle edema developed. Her past history was non-contributory.

Physical examination revealed a well developed, well nourished tall white woman, weighing 120 pounds. Her temperature was 98.7 F. and the pulse rate was 100. The blood pressure was 120/68. The following positive findings were present: Moderately enlarged lymph nodes noted in the axillary, inguinal and cervical regions, thyroid diffusely enlarged, a soft grade. . .



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