Primary Splenic Sarcomas of Hodgkin’s Type

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PRIMARY malignant disease of the spleen remains a rare entity despite improvements of diagnosis and more voluminous reporting in the literature with the passing of years. Hausmann and Gaarde1 reviewed the literature to 1940 and found a total of 178 cases, 9 of which they added from the Mayo Clinic. Twenty of these cases, however, were unconfirmed, the reports being-indexed but the journals unavailable.

From 1940 to 1945, 10 more cases appear in the literature. Two of these, 1 a primary sarcoma2 and the other a malignant hemangio-endothelioma also involving the liver,3 are reported in unavailable journals. Garlock4 reported an angiosarcoma; Goldberg,5 a malignant solitary hemangioma cavernosum, a solitary macrocystic lymphangioma, and a multiple macrocystic lymphangioma; Siirala and Näätänen,6 a primary malignant hemangioma with metastasis to the liver; Brule, Hillemand, and Isch-Wall,7 successful splenectomy for lymphoma of the spleen with uneventful four-year follow-up; Bon-ney,8 a lymphosarcoma; and Tomlinson,9 a primary microcystic lymphangioma.

We report 2 sarcomas of the spleen from Cleveland Clinic, bringing the total of reported cases of all types of primary splenic malignant disease to 190. These 2 cases constitute the only primary malignant tumors of the spleen seen at Cleveland Clinic in two decades. In 20,000 major surgical procedures, only 1 splenectomy for primary splenic malignant disease has been performed, as indicated in the second case report.

Case Reports

Case 1. A white man, aged 50, was seen in consultation with Dr. Perry King, Alliance, Ohio, with a history of persistent generalized lower abdominal pain of ten. . .



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