Sarcoma of the Stomach

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Between January, 1921, and January, 1945, 19 proved cases of gastric sarcoma were seen at Cleveland Clinic. Three have been described in previous publications. 1,2 Diagnoses have been confirmed by a recent review of microscopic sections in each case. The purpose of this report is to evaluate clinical features and diagnostic procedures, particularly roentgen and endoscopic examinations.

During the period covered by this study 1220 cases of malignant neoplasm of the stomach were seen at the Clinic, and 1.5 per cent were diagnosed as gastric sarcoma. Although this diagnosis is rare, when a biopsy reveals the presence of gastric sarcoma therapy may be more effective than in the case of carcinoma. An extensive review of the literature at the present time discloses the fact that from the standpoints of operability and curability sarcoma of the stomach is more amenable to surgical and roentgen therapy than carcinoma. However, an early diagnosis of sarcoma of the stomach may be more difficult than a diagnosis of carcinoma because, in contrast to the latter, involvement of the gastric mucosa may be a late development.


Ewing3 defines sarcoma as a malignant tumor composed of cells of the connective tissue type, classifying them according to histogenesis as lymphosarcoma, fibrosarcoma, and neurosarcoma. A majority of these tumors are characterized grossly by a fungating, soft, or fleshy structure.

We have chosen to use the following modification of Ewing's classification, suggested by Goldblatt:4

  1. Spindle cell myosarcoma

    1. Leiomyosarcoma

    2. Fibrosarcoma

    3. Neurofibrosarcoma (neurogenic sarcoma)

  2. Lymphosarcoma



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