Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Hypertension in Blacks Higher Through Middle Age

J Am Heart Assoc; ePub 2018 Jul 11; Thomas, et al

Blacks have a substantially higher risk for hypertension compared with whites through middle age, regardless of blood pressure (BP) in young adulthood, a recent study found. Researchers calculated the cumulative incidence of hypertension from age 18 to 55 years among participants in the CARDIA (Coronary Artery Risk Development in Young Adults) study. Incident hypertension was defined by the first visit with mean systolic BP ≥130 mmHg, or self-reported use of antihypertensive medication. Among the findings:

  • Among 3,890 participants (aged 18-30 years) without hypertension at baseline, cumulative incidence of hypertension by age 55 years was 75.5%, 75.7%, 54.5%, and 40.0% in black men, black women, white men, and white women, respectively.
  • Blacks had 1.5 to 2 times higher risk for hypertension after multivariable adjustment, regardless of baseline BP level.
  • Parental history of hypertension and higher body mass index were associated with a higher risk for hypertension among blacks and whites.


Thomas SJ, Booth III JN, Dai C, et al. Cumulative incidence of hypertension by 55 years of age in blacks and whites: The CARDIA study. [Published online ahead of print July 11, 2018]. J Am Heart Assoc. doi:10.1161/JAHA.117.007988.

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