Guideline target lipid level attainment is often poor in patients with symptomatic peripheral artery disease (PAD), although low-density lipoprotein cholesterol (LDL-C) levels did improve over the years 2010 to 2017 in a recent study. The single center observational study included 1,109 patients with symptomatic PAD and examined guideline equitable lipid lowering in this population. Researchers found:
- Target lipid level attainment was poor; only 27% reached the LDL-C goal of <70 mg/dL.
- LDL-C levels improved over the years 2010 to 2017; mean LDL-C 110 vs 80 mg/dL.
- LDL-C levels improved similarly (98 vs 84 mg/dL) intraindividually in 598 patients.
- PAD patient survival was better under statin therapy than when not under statin therapy (4% vs 11%).
Dopheide JF, Papac L, Schindewolf M, Baumgartner I, Drexel H. Poor attainment of lipid targets in patients with symptomatic peripheral artery disease. [Published online ahead of print February 27, 2018]. J Clin Lipidol. doi:10.1016/j.jacl.2018.02.013.