Among a large cohort of African Americans from the Jackson Heart Study, a large neck circumference (NC) was associated with increased risk for heart failure (HF) hospitalization, following adjustment for age and sex. Researchers included participants with recorded NC measurement at baseline (2000‒2004) and calculated age- and sex-adjusted cumulative incidence of clinical cardiovascular outcomes. They found:
- 5,290 participants were categorized into tertiles of baseline NC defined as ≤37 cm (n=2,179), 38‒40 cm (n=1,552), and >40 cm (n=1,559).
- After adjusting for age and sex, increasing NC was associated with increased risk of HF hospitalization (cumulative incidence = 13.4% in the largest NC tertile vs 6.5% in the smallest), but not mortality, stroke, myocardial infarction, or coronary heart disease.
- However, this risk was not statistically significant after adjusting for other clinical variables.
Pumill CA, Bush CG, Greiner MA, et al. Neck circumference and cardiovascular outcomes: Insights from the Jackson Heart Study. [Published online ahead of print March 8, 2019]. Am Heart J. doi:10.1016/j.ahj.2019.03.001.